Creating a toy data set | Implementing MR-SimSS with mr_simss | Comparing MR-SimSS with classical Two-Sample MR methods | Additional mr_simss parameters | Performing mr.simss with real data | Same-trait empirical analysis with TwoSampleMR package

Introduction | Intuition for MR-SimSS framework | Individual-level: | How does MR-SimSS work? | Assumptions made by MR-SimSS | Notation

Winner's Curse in MR | What is Winner's Curse bias? | How and why does Winner's Curse bias affect MR causal effect estimates? | Empirical evidence for the impact of Winner's Curse on MR estimates | How is Winner's Curse bias typically avoided in summary-level MR studies? | Weak Instrument Bias in MR | What is weak instrument bias? | How does weak instrument bias impact MR causal effect estimates? | Summary